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Although single binary markers of senescence commitment have long been used in preclinical research, their utility as clinical parameters have so far been limited due to the wide-ranging heterogeneity of senescence in vivo , which often renders estimates of senescent cell quantification imprecise

older athletic participants who had at least 3 h of exercise per week lasting one year, exhibited similar NAD + levels as healthy young participants

Together, these findings illustrate definitive spinal cord injury with very small spontaneous improvements in functional loss

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